Best Strains for Inflammation
Target chronic inflammation with strains rich in anti-inflammatory cannabinoids and terpenes like caryophyllene and myrcene.
Ranked from 2,796 strains tagged for inflammation in the StrainCompass database.
Disclaimer: This content is for informational purposes only. Consult a healthcare professional before using cannabis medicinally.
What 2,796 inflammation strains have in common
62% are hybrid, with an average listed THC of 19.5%. The most common terpenes are caryophyllene, myrcene and linalool.
Why these strains work
Inflammation is where CBD and caryophyllene earn their reputation. Caryophyllene binds the CB2 receptors that regulate immune response, and CBD is the cannabinoid most studied for anti-inflammatory effects, so CBD-rich and balanced strains punch above their THC weight in this category. Pinene and humulene round out the profile reviewers associate with stiffness and swelling.
Top 20 Strains for Inflammation
Ranked by how strongly users report relaxed effects, weighted by popularity. Strains verified by two or more sources rank first.
Blackberry Kush
Blackberry Kush is an easy-to-grow, 80% indica from Dutch Passion with 23% THC, offering sweet berry flavors and a relaxing body high.
LA Affie
LA Affie, an easy-to-grow indica, delivers relaxed and sleepy effects with earthy, diesel, and pine flavors, featuring up to 21% THC.
Shark
Shark is an easy-to-grow, 80% indica strain from CBD Seeds that offers sweet diesel notes and a heavy, sleepy body high.
Boss OG
Boss OG is a balanced 50/50 hybrid from Dark Heart Nursery with a piney diesel flavor, delivering a relaxing body high and calming effects.
Bubba's Gift
Bubba's Gift blends Bubba Kush and Gift of Aurora into a 70% indica with pine-spice flavor, easing insomnia, pain, and inflammation.
Chemdawg
Chemdawg, a sativa-dominant hybrid (OG Kush x Chemdawg 4), offers pine and diesel flavors with happy, creative effects and 12-22% THC.
9 Pound Hammer
9 Pound Hammer is a heavy indica with earthy berry notes, providing soothing relief for pain, inflammation, and insomnia.
Canadian Kush
Canadian Kush is an easy 90% indica hybrid with relaxed, sleepy effects, piney flavor, and THC between 19 and 21%.
Big Bazooka
Big Bazooka is a potent 70% indica hybrid from Big Bud x Jack Herer, delivering relaxed body high effects and spicy, diesel, sweet flavors.
Chem Valley Kush
Chem Valley Kush is a 50/50 hybrid of Chemdawg x SFV OG/Afghan with a sprawling terpene list and 21.6-23.79% THC.
More strains for inflammation
What to look for in a inflammation strain
- Meaningful CBD, from a few percent up to CBD-dominant
- Caryophyllene as a top terpene, ideally with humulene or pinene
- Balanced THC:CBD hybrids for daytime use without heavy impairment
- "Relaxed" and "Body high" as the dominant reported effects
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Inflammation strain FAQ
Is CBD or THC better for inflammation?›
CBD has the larger body of research for inflammation and does not impair, so CBD-rich strains are the usual starting point. THC is reported to help with the pain that accompanies inflammation. Many users prefer a balanced strain for both effects during the day.
Which terpene is anti-inflammatory?›
Beta-caryophyllene stands out because it activates CB2 receptors, which are involved in immune signalling, and it has shown anti-inflammatory activity in animal studies. Humulene, pinene, and myrcene are also studied for anti-inflammatory properties.
Do people use cannabis for arthritis?›
Arthritis is one of the most common reasons people cite for medical cannabis, and users typically report using balanced or CBD-rich strains for daytime stiffness and higher-THC strains for pain at night. Evidence from controlled trials is still limited; discuss it with your doctor, especially alongside other medications.
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